Montelukast-associated Churg-Strauss syndrome

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Montelukast-associated Churg-Strauss syndrome.

A 68-year-old asthmatic presented markedly unwell with arthralgia, mononeuritis multiplex, peripheral neuropathy, and eosinophilia. His past medical history included perennial rhinitis, and nasal polyps. Three months prior to admission his prednisolone was stopped and Montelukast was started. The diagnosis of Montelukast-associated Churg-Strauss syndrome was made. The drug was stopped and stero...

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[Churg-Strauss syndrome associated with montelukast].

A 47 year old woman who had a history of asthma for 15 years referred to our hospital because of infiltrates on her chest radiograph that not responded to antibiotic treatment. We found that she had eosinophilia in peripheral blood (38%) and bronchoalveolar lavage (54%), nasal polyposis, and transient pulmonary infiltrates, and in the base of these findings we diagnosed as Churg-Strauss Syndrom...

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Montelukast and Churg-Strauss syndrome

I read with interest the case report by Tuggey and Hosker where Churg-Strauss syndrome was associated with the use of montelukast in an asthmatic patient in whom there was no recent exposure to oral corticosteroid. However, it is worth noting that the patient was using a high dose of inhaled fluticasone propionate (1.5 mg/day) via a large volume spacer prior to the introduction of montelukast. ...

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Montelukast and Churg-Strauss syndrome.

Shanghai, China, postulated that MVP may have been the result of structural damage and functional derangement caused by the underlying vasculitis of BD. Whereas the association of MVP and BD may be either causally related or coincidental, it is important to keep in mind that, although BD is relatively rare in the United States, MVP is very common. BD occurs most frequently in Japan and in the M...

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Montelukast and Churg-Strauss syndrome

Several cases of eosinophilic conditions including ChurgStrauss syndrome (CSS) have recently been reported in asthmatic patients being treated with antileukotriene receptor antagonists. One patient with CSS who experienced a clinical relapse after treatment with montelukast and two asthmatic patients who developed CSS while receiving montelukast treatment are described. In one case reduction in...

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ژورنال

عنوان ژورنال: Age and Ageing

سال: 2003

ISSN: 0002-0729,1468-2834

DOI: 10.1093/ageing/afg076